The Cubs are giving the pill to Shota Imanaga who has a sizzling 0.78 ERA with a 0.75 WHIP through six starts. The Padres are starting 25-year-old righty Randy Vasquez who has surrendered four runs in each of his two MLB starts this year. Vasquez didn't even look good at Triple-A El Paso, pitching to a 8.40 ERA with a 1.87 WHIP in four starts. The Padres have been hitting the ball well over the last week but there isn't much of a gap between the offensive production of these sides. The Friars have also struggled against southpaws like Imanaga batting just .201 with an OPS of .650. With the Cubs averaging 3.24 runs per game at home through the first five innings and have the far better pitcher, back them to grab an early lead.