NFL Week 13 Odds and Betting Lines: Burrow-Less Bengals In Deep Against Jacksonville

The NFL odds enter the post-Thanksgiving landscape in Week 13, meaning the pressure packs on for teams vying for playoff positions. As for those clubs with uncertain futures, NFL Week 13 odds tread lightly based on their motivation heading into these matchups.

With all but one game left to play, the Week 13 slate comes to a close on Monday Night Football as the Jacksonville Jaguars are favored by double digits against the Joe Burrow-less Cincinnati Bengals.

Here's a look at the opening NFL Week 13 odds and the early adjustments. 

NFL Week 13 odds, lines, and spreads

These are the live NFL odds for Week 13, highlighting the best odds available from regulated sportsbooks within your area.

Seahawks vs. Cowboys odds

Opening line

• Cowboys -7
• Over/Under 46
• View full Seahawks vs. Cowboys line movement
• Read our Seahawks vs. Cowboys picks and predictions 

These teams played on Thanksgiving Thursday but received contrasting results. Seattle got slammed by San Francisco while Dallas dominated Washington. That has the Cowboys opening as touchdown faves in Week 13, with that spread jumping as high as -8 on Sunday night. The total hit the board at 46 points at most shops.

Also see: full Thursday Night Football odds

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Chargers vs. Patriots odds

Opening line

• Patriots +6
• Over/Under 39.5
• View full Chargers vs. Patriots line movement
• Read our Chargers vs. Patriots picks and predictions

Both teams come into this contest off Week 12 losses. The Patriots lost 10-7 to the New York Giants and the Chargers dropped a 20-10 decision to the Baltimore Ravens. Oddmakers opened the Chargers as 6-point road favorites with a total of 39.5.

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Lions vs. Saints odds

Opening line

• Saints +3
• Over/Under 44.5
• View full Lions vs. Saints line movement
• Read our Lions vs. Saints picks and predictions 

Some bookies opened the Lions as 3-point road chalk in NOLA while other shops came a bit later with -3.5. Those are turning into Detroit -4 as of Sunday evening. The Lions have had 10 days to get right after a bad Thanksgiving Thursday showing and the Saints have big-name injuries on both sides of the ball.

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Falcons vs. Jets odds

Opening line

• Jets +2.5
• Over/Under 35
• View full Falcons vs. Jets line movement
• Read our Falcons vs. Jets picks and predictions 

Post-Wilson life is just as bad a Pre-Wilson life for the Jets, who took one on the chin from the rival Dolphins this past Friday. As for Atlanta, it won a crucial divisional game against the Saints and seems to be figuring out something on offense, averaging 24.5 points in the past four games. The Falcons opened -2.5 and we could see -3 across the industry by Monday afternoon.

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Cardinals vs. Steelers odds

Opening line

• Steelers -6.5
• Over/Under 39
• View full Cardinals vs. Steelers line movement
• Read our Cardinals vs. Steelers picks and predictions 

Kyler Murray has made little difference to the Cardinals' success since returning from injury. Arizona was as short as a 3.5-point road underdog on the look-ahead line, but after getting rolled by the Rams while Pittsburgh picked off the shorthanded Bengals, this line opened Steelers -6.5. It sits at -6 at most books as of Sunday night.

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Colts vs. Titans odds

Opening line

• Titans +1.5
• Over/Under 42.5
• View full Colts vs. Titans line movement
• Read our Colts vs. Titans picks and predictions 

The look-ahead line for this AFC South showdown was Titans -1.5 but after the Colts crushed Tampa Bay and Tennessee crept past Carolina, the market has flipped. Indianapolis opened at -1.5 and is up to -2 across many books on Sunday night. 

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Dolphins vs. Commanders odds

Opening line

• Commanders +9.5
• Over/Under 49.5
• View full Dolphins vs. Commanders line movement
• Read our Dolphins vs. Commanders picks and predictions 

Washington got waxed on Thanksgiving Thursday and fired its defensive coordinator just in time for this non-conference clash with the Dolphins in Week 13. The look-ahead line was Miami -6.5 but oddsmakers tacked on an extra field goal after the Fins flattened the Jets on Black Friday. This opener is Miami -9.5 with the total hitting the board at 49.5 points. Both of those numbers are on the rise Sunday night.

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Broncos vs. Texans odds

Opening line

• Texans -3
• Over/Under 44.5
• View full Broncos vs. Texans line movement
• Read our Broncos vs. Texans picks and predictions 

A few weeks ago, no one would have given a rat's ass about this game. But with the Broncos on a five-game run and the Texans flirting with a wild-card ticket, this AFC Sunday showdown holds plenty of weight across the conference. The look-ahead line was Houston -3 and even with the Texans taking a tumbler to the Jaguars, books have stuck with the field goal spread.

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Panthers vs. Buccaneers odds

Opening line

• Buccaneers -6.5
• Over/Under 39
• View full Panthers vs. Buccaneers line movement
• Read our Panthers vs. Buccaneers picks and predictions 

A battle at the bottom of the worst division in football. Yuck. The Buccaneers opened as high as 6.5-point home chalk but the early action doesn't agree and has taken this NFC South spread to Tampa Bay -5.5 in the first few hours. The total opened at 39 and is down to 38 points.

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Browns vs. Rams odds

Opening line

• Rams -4.5
• Over/Under 38
• View full Browns vs. Rams line movement
• Read our Browns vs. Rams picks and predictions 

The look-ahead line was Rams +1 but with the Browns potentially losing QB Dorian Thompson-Robinson, WR Amari Cooper, and star DE Myles Garrett to injuries in Week 12, bookies reopened with Los Angeles as a 4.5-point home fave. 

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49ers vs. Eagles odds

Opening line

• Eagles +1
• Over/Under 45.5
• View full 49ers vs. Eagles line movement
• Read our 49ers vs. Eagles picks and predictions 

The main event of Week 13 opened shortly after the Eagles escaped overtime with a rainy win over the Bills on Sunday. Books pegged this one as short as a pick'em with others giving a slight nod to San Francisco -1. That spread has since climbed to 49ers -2, with the visitor enjoying 10 days off after winning on Thursday and some notable injuries to the Eagles defense. The total is bouncing between 45.5 and 46.5 on Sunday night. 

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Chiefs vs. Packers odds

Opening line

• Packers +7
• Over/Under 42
• View full Chiefs vs. Packers line movement
• Read our Chiefs vs. Packers picks and predictions 

Kansas City opened as a touchdown favorite in Lambeau Field but with the Cheeseheads getting a 10-day gap in action thanks to their big win at Detroit on Thursday, this spread has come off the key number and sits Chiefs -6.5 on Sunday night. The total opened at 42 and has climbed as high as 43 points. FYI: keep an eye on the forecast for Sunday Night Football. Could be a classic Wisconsin winter in Week 13.

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Bengals vs. Jaguars odds

Opening line

• Jaguars -7.5
• Over/Under 40/5
• View full Bengals vs. Jaguars line movement
• Read our Bengals vs. Jaguars picks and predictions (coming soon)

Jacksonville slayed the ghost of AFC South past with a huge win over Houston in Week 12 and now gets the Monday stage against the Burrow-less Bengals. Cincinnati struggled under QB2 Jake Browning in the loss to Pittsburgh and opened on the other side of a touchdown at +7.5. That spread has swelled to Jags -8 as of Sunday night.

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More weekly NFL odds content

• Week 1 odds
• Week 2 odds
• Week 3 odds
• Week 4 odds
• Week 5 odds
• Week 6 odds
• Week 7 odds
• Week 8 odds
• Week 9 odds
• Week 10 odds
• Week 11 odds
• Week 12 odds
• Week 14 odds
• Week 15 odds
• Week 16 odds
• Week 17 odds
• Week 18 odds

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