As everyone still recovers from turkey comas, the NFL Week 12 odds board is winding down.
Only the clash between the Chicago Bears and Minnesota Vikings on Monday Night Football remains with the hometown Vikes favored by a meager field goal.
Below, I run down the opening odds and early adjustments to the Week 12 NFL odds finale.
NFL Week 12 odds, lines, and spreads
These are the live NFL odds for Week 12, highlighting the best odds available from regulated sportsbooks within your area.
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Packers vs. Lions odds
Opening line
- Lions -7.5
- Over/Under 45.5
- View full Packers vs. Lions line movement
- Read our Packers vs. Lions picks and predictions
The Lions host their annual Thanksgiving Thursday game, laying 7.5 points against the rival Packers in Week 12. This total opened as low as 45 points and is now up to 46 O/U in the first hours of action Sunday night. Green Bay will likely be without RB Aaron Jones who left Week 11 with a knee injury.
Also see: full Thursday Night Football odds
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Commanders vs. Cowboys odds
Opening line
- Cowboys -11
- Over/Under 47
- View full Commanders vs. Cowboys line movement
- Read our Commanders vs. Cowboys picks and predictions
Dallas welcomes Washington for its yearly Turkey Day homestand on Thursday. The Cowboys opened as 11-point home favorites and the total hit the board at 47 points before jumping to 48 O/U. Just an FYI: Dallas is 1-11 ATS in its last dozen Thanksgiving games.
Also see: full Thursday Night Football odds
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49ers vs. Seahawks odds
Opening line
- Seahawks +5.5
- Over/Under 43
- View full 49ers vs. Seahawks line movement
- Read our 49ers vs. Seahawks picks and predictions
San Francisco opened as low as -5.5 for this final Thursday game and the market has moved as far as -7 in the first hour of action. Seattle QB Geno Smith is nursing an elbow injury and RB Kenneth Walker III is questionable on the short week as well.
Also see: full Thursday Night Football odds
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Dolphins vs. Jets odds
Opening line
- Jets +7.5
- Over/Under 42
- View full Dolphins vs. Jets line movement
- Read our Dolphins vs. Jets picks and predictions
We get a Black Friday matchup between the Dolphins and Jets, with Miami opening as a 7.5-point road favorite. New York's QB situation is cloudy with Zach Wilson getting benched in Week 11's loss to Buffalo. This total is dropping because of it, slimming from 42 to 41 points.
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Saints vs. Falcons odds
Opening line
- Falcons -1
- Over/Under 41.5
- View full Saints vs. Falcons line movement
- Read our Saints vs. Falcons picks and predictions
These NFC South foes are both coming off much-needed bye weeks, with Atlanta hitting the board as slim 1-point chalk at most books. Other shops are dealing pick'em. The Falcons will have Desmond Ridder back under center after being benched briefly. The Saints have injury concerns around QB Derek Carr, WR Michael Thomas, and top CB Marshon Lattimore.
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Steelers vs. Bengals odds
Opening line
- Bengals +1
- Over/Under 34.5
- View full Steelers vs. Bengals line movement
- Read our Steelers vs. Bengals picks and predictions
The Bengals begin life without Joe Burrow against the rival Steelers and their dangerous defense. With Burrow out for the season due to a wrist injury, backup QB Jake Browning takes over the offense. The look-ahead line was Cincinnati -6 with the total at 41.5. The official Week 12 opener is very different, with Cincy set as 1-point home underdogs and the total down to 34.5 points.
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Jaguars vs. Texans odds
Opening line
- Texans -1
- Over/Under 46
- View full Jaguars vs. Texans line movement
- Read our Jaguars vs. Texans picks and predictions
This AFC South showdown had Houston opened between -1 and +1.5 across the industry Sunday night, with shops reaching a market consensus of pick'em later in the evening. This total has also seen movement, with the opening O/U of 46 points up to 47.5 at some sharper online books.
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Buccaneers vs. Colts odds
Opening line
- Colts -1
- Over/Under 42
- View full Buccaneers vs. Colts line movement
- Read our Buccaneers vs. Colts picks and predictions
This is another spread that opened at different marks across various books Sunday night, with Indianapolis anywhere from -1 to -2.5. The Colts are coming off the bye week while Tampa Bay travels for the second straight week and lost some key defenders in LB Lavonte David and DBs Carlton Davis and Jamel Dean to injury in Week 11.
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Patriots vs. Giants odds
Opening line
- Giants +3.5
- Over/Under 34.5
- View full Patriots vs. Giants line movement
- Read our Patriots vs. Giants picks and predictions
The Patriots opened as 3.5-point road favorites in East Rutherford in Week 12 facing a Giants team riding high off an upset win over Washington in Week 10. Keep a close eye on the injury report from New York with a number of players sitting out this past Sunday. New England is coming off the bye and was a 5.5-point favorite on the look-ahead line.
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Panthers vs. Titans odds
Opening line
- Titans -4
- Over/Under 37.5
- View full Panthers vs. Titans line movement
- Read our Panthers vs. Titans picks and predictions
Tennessee opened as a 4-point home favorite in this battle of rookie QBs, which is why this total opened at 37.5 and is down to 36.5 at some sharp online markets. The Titans have also come down to -3.5 at some shops on Sunday night.
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Rams vs. Cardinals odds
Opening line
- Cardinals +2.5
- Over/Under 45.5
- View full Rams vs. Cardinals line movement
- Read our Rams vs. Cardinals picks and predictions
Los Angeles opened as high as -2.5 but with WR Cooper Kupp questionable thanks to an ankle injury, early play is on Arizona and slimming this spread to Rams -1. This total opened at 45.5 points and is up to 46.5 at some books.
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Browns vs. Broncos odds
Opening line
- Broncos -2.5
- Over/Under 35.5
- View full Browns vs. Broncos line movement
- Read our Browns vs. Broncos picks and predictions
DTR and the surprising Cleveland Browns pulled off at 13-10 victory over the Pittsburgh Steelers in Week 11, and roll into Denver as 2.5-point road underdogs for Sunday afternoon's contest. The Broncos are coming off a 21-20 win over the Minnesota Vikings, and Sean Payton's team is starting to put things together as they approach the back half of the regular season. Oddsmakers opened the total for Sunday's game at 35.5.
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Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
Chiefs vs. Raiders odds
Opening line
- Raiders +9.5
- Over/Under 43.5
- View full Chiefs vs. Raiders line movement
- Read our Chiefs vs. Raiders picks and predictions
The Chiefs hit the road following their disappointing 21-17 loss at home on Monday Night Football to the Philadelphia Eagles. The Raiders are coming off a respectable 20-13 loss in Miami against the Dolphins. Las Vegas held the high-flying fish to only six points in the second half - the problem is that Aidan O'Connell and the Raiders scored ZERO points in that same second half. Oddsmakers opened the Chiefs as big 9.5-point road favorites with a total of 43.5.
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Bills vs. Eagles odds
Opening line
- Eagles -3
- Over/Under 48
- View full Bills vs. Eagles line movement
- Read our Bills vs. Eagles picks and predictions
The Eagles looked great in their 21-17 road win over the Kansas City Chiefs on Monday Night Football. Philly will now return home to face another tough opponent with the Buffalo Bills landing at the LINC for a high-profile Sunday afternoon showdown. Oddsmakers opened the Eagles at -3 with a total of 48.
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Ravens vs. Chargers odds
Opening line
- Chargers +4
- Over/Under 45.5
- View full Ravens vs. Chargers line movement
- Read our Ravens vs. Chargers picks and predictions
The Ravens get a mini-bye before this Sunday Night Football showdown in Los Angeles. Books opened Baltimore as a 4-point favorite and this total opened as low as 45.5, jumping to 46.5. The struggling Chargers defense suffered injuries to LBs Joey Bosa and Tanner Muse at the wrong time, with Lamar Jackson and the Ravens running over opponents.
Also see: full Sunday Night Football odds
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Bears vs. Vikings odds
Opening line
- Vikings -4
- Over/Under 45.5
- View full Bears vs. Vikings line movement
- Read our Bears vs. Vikings picks and predictions
Just what everybody is clamouring for, another primetime game for the Chicago Bears. The Bears looked good but gave up the game late in Week 11 against the Detroit Lions, and the Vikings dropped a tough one against Russell Wilson and the Denver Broncos. Oddsmakers opened the Vikes as 4-point home favorites for Monday Night Fotball with a total of 45.5.
Also see: full Monday Night Football odds
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