Time is running out for the Chicago White Sox.
They sit six games back of the AL Central-leading Cleveland Guardians and 5.5 back of the final Wild Card spot heading into Thursday's matchup.
If that weren't bad enough news, they face Shane Bieber tonight — one of the MLB's most consistent starters.
With the help of EV Analytics, a cutting-edge sports analytics company trusted by fans and sports media outlets to help make informed, data-driven decisions, we're breaking down the Guardians vs White Sox to find you the best possible betting angles.
Make your best MLB picks for September 22 by loading up on the latest MLB odds, betting insights, and trends below.
Guardians vs White Sox odds
This odds widget represents the best odds available for each betting market from regulated sportsbooks.
Use the live odds widget above to track any future line movements right up until first pitch and be sure to check out the full MLB odds before placing your bets.
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Guardians vs White Sox insights & trends for September 22
The following insights and trends are powered by WriteNow™ and EV Analytics.
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