Week 10 in the CFL wraps up on Saturday with a pair of games in Alberta, and the first contest will take place between the BC Lions and Calgary Stampeders.
This should be an entertaining duel between two of the best teams and quarterbacks in the league with Bo Levi Mitchell and the 5-2 Stamps hosting Nathan Rourke and the 6-1 Leos.
Here are our best Lions vs. Stampeders picks and predictions for Saturday, August 13.
Lions vs Stampeders odds
This odds widget represents the best odds available for each betting market from regulated sportsbooks.
Oddsmakers were expecting a close contest with CFL betting lines opening with the Stampeders as slim half-point home dogs, but that line has since grown to +3 with some books still offering the Lions at -2.5. The Over/Under opened at a season-high 53.0 and has since been bet up to 53.5.
Use the live odds widget above to track any future line movements right until kickoff and be sure to check out the full CFL odds before betting to ensure you get the best number.
Lions vs Stampeders Week 10 predictions
Predictions made on 8/12/2022 at 1:30 p.m. ET.
Click on each prediction to jump to the full analysis.
Lions vs Stampeders game info
• Location: McMahon Stadium, Calgary, AB
• Date: Saturday, August 13, 2022
• Kickoff: 7:00 p.m. ET
• TV: TSN
Lions at Stampeders betting preview
Weather
Key injuries
Lions: Delvin Breaux Sr. DB (Questionable), James Butler RB (Questionable), Quincy Mauger DB (Questionable), David Knevel G (Out), Woody Baron DT (Out), Steven Richardson DT (Out), Boseko Lokombo LB (Out).
Stampeders: Tre Roberson CB (Out), Ka'Deem Carey RB (Out), Jameer Thurman OLB (Out), Malik Henry WR (Questionable), Sean McEwan C (Out), Branden Dozier DB (Questionable), Javien Elliott DB (Out).
Find our latest CFL injury reports.
Betting trend to know
BC is 7-2 ATS in its last nine road games, while Calgary is 1-4 ATS in its previous five contests at home. Find more CFL betting trends for Lions vs. Stampeders.
Lions vs Stampeders picks and predictions
Our side and total predictions are based upon our analysis of the line and total in this game. Our best bet is our favorite pick across all markets.
Spread analysis
The West Division has featured the three most impressive teams in the CFL this year, with the BC Lions and Calgary Stampeders having only lost to the defending champion Blue Bombers.
It's been an exciting season for Lions fans, who have witnessed the emergence of 24-year-old Canadian quarterback Nathan Rourke. Rourke easily leads the league in passing yards per game (345.4), yards per pass attempt (10.5), completion percentage (81.3%), efficiency rating (133.2), and passing touchdowns (21). He's also used his legs when needed, adding another 233 yards and five scores on the ground.
He leads the league's best offense, but the Lions' defense has also been terrific. They've allowed the fewest yards per game (279.3) while ranking second in sacks and takeaways per game. BC is been particularly dominant in the secondary, as they currently hold opposing QBs to the fewest yards per pass attempt and lowest efficiency rating in the league.
That could make it tough for Calgary QB Bo Levi Mitchell to move the ball. Mitchell is a two-time CFL MOP winner, but he's been inconsistent this year and is coming off an ugly outing against the Redblacks where he completed just 13 of 27 passes for 137 yards.
On the other side of the ball, Calgary has been very stout, holding opponents to 5.9 yards per play which isn't too far behind BC's league-leading 5.6 yards per play. That said, they don't generate much pressure on opposing QBs, and they recently lost their best cover man Tre Roberson to a season-ending knee injury.
That's bad news against a Lions attack that is loaded with weapons, especially after All-Star wide receiver Bryan Burnham returned to the lineup last week after a month-long absence.
Based on what we've seen so far this season, BC clearly has the better aerial attack and the superior pass defense, which is critical in the pass-heavy CFL. That's enough for me to back the Lions on the spread.
Prediction: Lions -2.5 (-110 at bet365)
Over/Under analysis
This O/U hit the board at 53.0, the season's highest total, and has since ticked up to 53.5. Despite that big number, I'm still leaning towards the Over with how high-powered these offenses are capable of being.
Mitchell had an off-night in Week 9, which resulted in a low-scoring 17-3 victory. Still, the Over remains 6-2 in the Stamps' last eight games. They've also scored at least 28 points in five of seven games this season. While running back Ka'Deem Carey is out with a hamstring injury, backup Dedrick Mills exploded for 100 yards on 16 carries last week.
Meanwhile, the Over has gone 10-2-1 in the Leos' last 13 games, and they've put up at least 32 points in five of seven games this year.
Prediction: Over 53.5 (-110 at FanDuel)
Best bet
You never want to get a line at its worst point. While I was more gung-ho about taking the Lions at -1, I'm still confident in backing them at anything under that key number of 3.
The Lions have been the better team on both sides of the ball this season, and home-field advantage isn't nearly a big enough factor for me to consider the Stamps on this short line.
Pick: Lions -2.5 (-110 at bet365)
Did you know that if you parlayed this week’s CFL Lions vs. Stampeders picks, you could win $26.45 on a $10 bet?
Use our CFL parlay calculator to create your own parlays and see their potential payouts.